Core instrumentation and main applications:
- ATUMTome /SEM
- SEM imaging of serial sections and 3D reconstruction
- Connectomics – reconstruction of neurons and synapses in close collaboration with the Research Unit Electron Microscopic Techniques (EMT) at the Division of Cell Biology, Histology and Embryology
- Tecnai 20 - Analytical TEM (performed together with the Research Unit EMT) - Detection of chemical elements within cells and tissues
Other applications:
- Correlative Light and Electron Microscopy (C.L.E.M.; performed together with Core Facility Imaging) combines the capabilities of two typically separate microscopy platforms (e.g. light and electron microscopy) to sequentially image the same cell/structure exploiting the advantages of both technologies
- Immunogold labelling techniques to localize antigens within tissues or cells at highest optical resolution
- High-pressure freezing in combination with Cryo-SEM to preserve functional characteristics of ultrastructures
