Center for Medical Research

Science-Technology Interface: Structural Biology

The Science-Technology Interface: Structural Biology (STI:SB) acts as a link between technology, research and translation. It supports and connects structural biologists and those who are interested in structural biology and its application in biomedical research.

Bridging Science and Technology

The Science-Technology Interface: Structural Biology helps to establish new co-operations and gives advice on which technique(s) might be possible and useful for research related to

  • structure-function relationships of biomolecules, proteins, nucleic acids, metabolites, biomolecular complexes or other large assemblies
  • molecular structure and dynamics in cellular compartments, organelles or cellular interactions
  • (molecular) changes in relation to health and disease or in context with aging and environmental factors 
  • target validation and rational drug design.

Connecting Integrative Structural Biology and Medical Research

STI:SB connects different research areas and technologies, such as biochemistry, biophysics, cryo-electron microscopy, hydrogen-deuterium exchange mass spectrometry, integrated metabolism research, molecular modelling, nuclear magnetic resonance spectroscopy, small-angle X-ray scattering, small-angle neutron scattering, X-ray crystallography and others.

STI:SB also supports computational work related to 3D-reconstruction, modelling and visualisation.



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