Center for Medical Research

Science-Technology Interface: Structural Biology

The Science - Technology Interface: Structural Biology (STI:SB) acts as a link between technology, research and translation. It supports and connects structural biologists and those who are interested in structural biology and its application in biomedical research.


Bridging Science and Technology/Medical Structural Biology

STI:SB gives advice on which technique(s) might be possible and useful for research related to

  • structure-function relationships of biomolecules, proteins, nucleic acids, metabolites, biomolecular complexes or other large assemblies
  • molecular structure and dynamics in cellular compartments, organelles or cellular interactions
  • (molecular) changes in relation to health and disease or in context with aging and environmental factors 
  • target validation and rational drug design.

It also acts as interlink between structural biology and biomedical/clinical research and assists researchers in finding new partners and co-operations for their interdisciplinary scientific work.


Integrative Structural Biology and Biophysics

STI:SB connects and supports different research areas and technologies, such as X-ray crystallography, nuclear magnetic resonance spectroscopy, cryo-electron microscopy, small-angle X-ray scattering, molecular modelling, hydrogen-deuterium exchange mass spectrometry, integrated metabolism research, biophysics, biochemistry and others. It also supports computational work related to data analysis, 3D-reconstruction, modelling and visualisation.




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