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Core instrumentation and main applications:

  • ATUMTome /SEM
    • SEM imaging of serial sections and 3D reconstruction
    • Connectomics – reconstruction of neurons and synapses in close collaboration with the Research Unit Electron Microscopic Techniques (EMT) at the Division of Cell Biology, Histology and Embryology
  • Tecnai 20 - Analytical TEM (performed together with the Research Unit EMT) - Detection of chemical elements within cells and tissues

Other applications:

  • Correlative Light and Electron Microscopy (C.L.E.M.; performed together with Core Facility Imaging) combines the capabilities of two typically separate microscopy platforms (e.g. light and electron microscopy) to sequentially image the same cell/structure exploiting the advantages of both technologies
  • Immunogold labelling techniques to localize antigens within tissues or cells at highest optical resolution
  • High-pressure freezing in combination with Cryo-SEM to preserve functional characteristics of ultrastructures

 

 

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