Considerable effort has been invested in the development of a modular organisational structure to maximize effectiveness. To ensure maximum efficiency, candidate projects are critically reviewed by an independent commission and access is awarded to clinical research groups for the duration of the project funding period. In addition to the labs directly allocated to a specific project, any further infrastructure at the ZMF (isotope lab, SL2 and SL3 cell-culture labs, immunohistochemistry unit, etc.) may be utilized by the project personnel. Six Core Facilities (Molecular Biology, Mass Spectrometry, Imaging, Clinical Research Center, Computational Bioanalytics, and Ultrastructure Analysis/Electron microscopy) provide access to instruments, technologies, methods, services, as well as expert consultation and other services for scientific and clinical investigators.