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CF MS - adobestock.com/MZ-generiert-mit-KI

cf-ms Core Facilities Center for Medical Research Research Infrastructure OU Organizational units Medical University of Graz

Instruments & Applications

The Core Facility has a state-of-the-art equipment infrastructure that enables comprehensive molecular characterization of biological samples.

Infrastructure

Instruments

Orbitrap Eclipse Tribrid (Thermo Scientific)
LTQ-Orbitrap Velos Pro (Thermo Scientific)
Q Exactive Focus (Thermo Scientific)
Orbitrap Exploris 480 (Thermo Scientific)
maXis II ETD(Bruker Daltonics)
MSD GC-MS (Agilent)
amaZon speed ETD (Bruker Daltonics)
Avance NEO 600 MHz NMR-Spectrometer (Bruker Biospin)

Applications

Isolation: on demand isolation of requested compound classes from different sample types
- Small molecule metabolites
- Lipids
- Proteins
Separation: comprehensive or target-optimized
- Liquid chromatography
- Gas chromatography
Acquisition: comprehensive or target-optimized mass spectrometry
- Ultra-high resolution (500.000)
- DDA MS2/M3 (deep profiling)
- DIA
Quantification:
- comprehensive, differential, semi-quantitative analysis
- absolute quantification of specific target compounds
Isotope tracing
Structure elucidation of individual purified compounds (i.e. metabolites, lipids)
Bioinformatics: tailored data processing strategies
- basic group statistics
- multivariate statistical analysis
- Enrichment analysis
- Pathway mapping
Multiomic integration