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Core Facility Ultrastructure Analysis provides services in ultrastructure research / electron microscopy. The established core technologies include transmission electron microscopy and scanning electron microscopy. A particular competence of the facility lies in the area of ultrastructural analysis of cryopreserved or fixed tissues or cells by means of a combination of serial section technology, electron tomography and 3D reconstruction.
Service
- Classical transmission / scanning electron microscopic methods such as immunogold localization
- 3D reconstruction of (sub-) cellular structures such as neurons and synapses (in close cooperation with the research unit electron microscopic techniques at the Department of Cell Biology, Histology and Embryology)
- Detection of chemical elements in subcellular compartments
- Correlative light and electron microscopy
Infrastructure
- High pressure freezing technology
- Automated serial production (ATUMTome / Zeiss)
- Transmission electron microscopes (e.g. FEI TECNAI)
- Scanning electron microscopes (e.g. Sigma500 / Zeiss)
Contact
